FRS3 Polyclonal Antibody, 50ul Pasteur Pipets The encoded protein has tyrosine

The encoded protein has tyrosine kinase activity and belongs to the src family of proteins

Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome

Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene

It is located close to translocation breakpoints associated with premature ovarian failure

FRS3 Polyclonal Antibody, 50ul Pasteur Pipets The encoded protein has tyrosineFRS3 encodes a substrate for the fibroblast growth factor receptor. Fibroblast growth factor receptor substrate 3 is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. Fibroblast growth factor receptor substrate 3 down regulates extracellular regulated kinase 2 through direct binding.